For two decades, Kambo has been the subject of medical research. Kambo contains bioactive peptides and neuropeptides, which are chains of amino acids responsible for performing different biological functions and have affinity and selectivity for binding with human cell receptor sites. Kambo has the ability to cross the blood-brain barrier, allowing it access to support a number of biological functions. Recent studies have shown that Kambo is one of the strongest natural anti-inflammatory, antibiotic, antimicrobial, and anesthetic substances, in addition to being one of the strongest and natural ways to strengthen the immune system. Antimicrobial peptides have been shown in studies to be effective against drug-resistant strains of bacteria, fungi, protozoa, parasites, and viruses.
Science is currently researching Kambo for applications to treat Chronic Fatigue Syndrome, Chronic Pain, Cancer, HIV, Parkinson’s Disease, Alzheimer’s, Depression, Blood Circulation and Vascular problems, Hepatitis, Diabetes, Rheumatism, Arthritis, Addictions, Migraines, Organ Diseases, and Skin and Eye issues. Research is focused on the identification, isolation, and reproduction of the actions pharmacological and effects of the bioactive peptides. Currently, there are no peer-reviewed papers on the use in human subjects; therefore, no claims can be made as to efficacy in the treatment of medical conditions.
The following explains some of the effects of the Kambo bioactive peptides:
- Phyllomedusin: a tachykinin acting as a neuropeptide that acts on the central nervous system, cardiovascular system, and immune system. It modulates serotonin, dopamine, and other neurotransmitters, produces contraction of smooth muscles such as the stomach, intestines, pancreas, gallbladder, bowels, tear ducts, and salivary glands, and is a potent vasodilator. It contributes to the purge process and defecation and may produce pulsating and pounding sensations during the Kambo process.
- Phyllokinin: a bradykinin that induces a long-lasting reduction in blood pressure .
- Phyllocaerulin: a neuropeptide that stimulates smooth muscle contraction of the heart, vascular, and gastrointestinal system, stimulates secretions from the stomach. Gallbladder, and pancreas, reduces blood pressure, and contributes to the purge process by stimulating nausea and vomiting, elevated heart rate, and abdominal discomfort. It works to decrease appetite, contributes to digestive improvement, and affects thermoregulation. It also has analgesic properties, which diminishes pain and fatigue while increasing strength and resistance.
- Phyllolitorin: a Bombesin peptide that stimulates gastric acid secretion and smooth muscle contractions. Active in the central and peripheral nervous systems, it affects thermoregulation, glucoregulation, satiety, circadian rhythm, sensory nerve transmission, energy homeostasis, immunological functions, respiratory and urogenital system effects, and the secretion of numerous hormones and neurotransmitters.
- Dermorphin: a heptapeptide of the sauvagine family, it induces potent analgesic and opiate-like effects, which have been shown to exceed those of morphine without the side-effects of tolerance and dependence. It functions like a hormone, interacting with the pituitary-adrenal axis and corticotropin-releasing receptors, which are involved in the mediation of the physiological reactions of exposure to stress, cortisol release, anxiety, depression, and addictive behaviors. It also affects smooth muscle contraction, tachycardia, and reduces blood pressure and inflammation.
- Deltorphin: a heptapeptide with the highest affinity and selectivity for binding with delta opioid receptors, is could be one of the most natural powerful pain killing substances, and is many more times potent than our own endogenous beta-endorphins.
- Dermaseptin: a family of peptides with potent antimicrobial activity against bacteria, fungi, yeasts, protozoa, and viruses, including HSV-1 and HSV-2. They have shown destructive action toward filamentous fungi responsible for debilitating infections that accompany immune-deficiency syndrome. Dermaseptin B2 (adrenoregulin) has been shown effective in killing certain types of cancer cells, by inhibiting the growth of tumor cells while also being cytotoxic towards the same cells. The dermaseptins are able to exterminate harmful cells using antimicrobial and anticancer mechanisms with no damage to or toxicity to healthy mammalian cells. The ability of adrenoregulin to affect the binding of agonists to adenosine receptors holds potential for the targeted treatment of depression, stroke and cognitive decline, Alzheimer’s , and Parkinson’s disease.
- Dermatoxin: peptides similar to dermaseptin, they are anti-bacterial towards gram positive eubacteria and to a lesser extent gram-negative eubacteria.
- Tryptophyllin: neuropeptides with anti-bacterial properties; recent studies have shown an anti-proliferative effect on three different prostrate cancer cell lines.
- Calcintonin Gene Related Peptide: a highly potent vasodilator, which research is suggesting may be beneficial in preventing the development of hypertension and cardiovascular pathologies. It also possesses protective mechanisms affecting would healing, arthritis, skin conditions, diabetes, and obesity.
- Skin Peptide Tyrosine: a peptide with potent antibiotic activity against strains of bacteria, fungi, and protozoa. Related peptides function to integrate a variety of important regulatory functions, such as sympathetic vascular control, central regulation of endocrine and autonomic function, food intake, circadian rhythm, and histamine release from isolated mast cells.
Kambo is a powerful detoxification process for the liver and intestines. Immediate and short-term effects include enhanced mood, alertness, clarity, focus, energy, and increased resistance to stress, tiredness, hunger, and thirst. The mind becomes still and everything becomes easier to manage. By empowering the immune system, natural functions are enhanced to existing health problems are improved or resolved and future ones are less likely to occur. Spiritually, it helps to overcome obstacles and release blockages on an emotional level. It clears the energy field and realigns the chakras, assisting in breaking negative habits to live and think more naturally.
While there is an abundance of research, we do not ensure any results or offer any kind of cure or healing. This is a ceremonial and spiritual experience of alignment and well-being.